Medicine Innovates Medicine Innovates: Delivering innovations in medicine to the world for better health and prosperity
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the Role of KCNB2 in SHH Medulloblastoma: A Path to Targeted Cancer Therapy
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Tumor-Stroma Interactions: How NSCLC and Radiotherapy Drive Resistance via MSC Senescence
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Proteomic Profiling for Optimized Therapy Selection in Acute Myeloid Leukemia
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Targeting NPEPPS to Enhance Cisplatin Efficacy: A Pathway to Overcome Chemotherapy Resistance
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Tri-Specific T-Cell Engagers for Glioblastoma: A Multivalent Immunotherapy Targeting Tumor Heterogeneity
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Early Post-Infusion Absolute Lymphocyte Count as a Prognostic Marker in BCMA-Targeting CAR-T Therapy for Relapsed Multiple Myeloma
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TMEM97 Drives Estrogen Receptor Activation and Tamoxifen Resistance via mTOR/S6K1 Signaling in Breast Cancer
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RRAS2: A Prognostic Biomarker Driving Postpartum Triple-Negative Breast Cancer
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Comprehensive Pancreatic Cancer Risk Prediction Model Integrating Genetic, Lifestyle, and Medical History Variables: Insights from the UK Biobank
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Propensity Score Matching Reveals Non-Significance of Male Sex as a Prognostic Factor in Differentiated Thyroid Cancer Post Iodine Treatment
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Unsupervised Machine Learning Helps Discover Patterns of Racial Disparities in Breast Cancer Patients
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Enhanced Diagnostic Accuracy of Tc-PSMA SPECT/CT vs. mpMRI in Prostate Cancer Staging and Relapse Detection
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Breaking Ground in CLL Research: Novel Mouse Model Unveils New Therapeutic Pathways
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PC4 Mediated Enhancement of NHEJ Repair Promotes Radioresistance in Hepatocellular Carcinoma
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Lung-Resident Memory T Cells and Epithelial Antigen Presentation Drive Neutrophilic Asthma: A Pathway for Targeted Therapy
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Immunotherapy in Primary Mediastinal Undifferentiated Pleomorphic Sarcoma: A Promising Approach
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Dual Mechanisms of NF-κB Activation in DNA Damage Responses: Bridging Transcriptional Stress and Inflammation
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Selective JAK1 Inhibition with Itacitinib Enhances Haploidentical Transplantation Outcomes by Mitigating GvHD and CRS
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Towards a True Universal Flu Vaccine: Broad Protection and Targeted Immune Activation Using Herpesvirus Vectors
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Environmental Cues in Naive CD4+ T Cell Differentiation: Type I Interferon-Driven Memory Cell Emergence and Its Implications for Immunotherapy
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Inflammation-Driven Phenoconversion: How CRP Levels Disrupt CYP2C19-Dependent Voriconazole Metabolism and Redefine Personalized Dosing
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Non-Infectious Extracellular Vesicles from Varicella Zoster Virus-Infected Neurons Suppress Antiviral Responses and Facilitate Secondary Pathologies
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Distinct Antigen-Presenting Cell Subsets as Key Regulators of Gut Immune Balance: Implications for Inflammatory Disease Management
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Exosome-Powered Oncolytic Viruses Change the Game in Breast Cancer Treatment
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Describing the Mosquito Effect: Intercellular Transfer of Cytoplasm in the Tumor Microenvironment and Its Potential Impact on T Cell Function
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Seasonal Patterns and Periodicity of COVID-19 Outbreaks in the United States: Discoveries from a Spectral Analysis Study
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ATF6: A Double-Edged Sword in Lysosomal Regulation and Mutant TP53 Degradation in Cancer Cells
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Fibulin-2: A Key Genetic Driver in Goldenhar Syndrome and Craniofacial Development
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The Essential Role of the PA14 Domain in B4GALNT3 and the Regulatory Impact of LacdiNAc on N-Glycan Biosynthesis
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β-Blockers as Potential Modulators of Huntington’s Disease Onset and Progression
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Chemotherapy-Driven Aging: Lasting Impacts of Cancer Treatment on Biological Aging Markers in Breast Cancer Survivors
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Nav1.5-Mediated Sodium Influx Drives Breast Cancer Metastasis Through Glycolytic Acidification
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Squalene Peroxidation in Acne Vulgaris: Linking Sebum Oxidation to Inflammation and Comedogenesis
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Impact of APOE Locus on Aging-Related Mitochondrial Function in Alzheimer’s Disease and Longevity
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Structural and Functional Insights into ORCA’s Role in Chromatin Organization and DNA Replication Initiation
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SOCS1 Regulation of Hepatic Stellate Cell Activation: Implications for Liver Fibrosis and Hepatocellular Carcinoma Development
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Unraveling the Web of Genomic Stability: Micronuclei, Mutations, and the Promise of New Therapies
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Rab2 Revealed: Deciphering the Golgi’s Role in Cancer through the Lens of Noncanonical Autophagy
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How p53 and MRE11 Dance in the Light of Disorder and Modification
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Rethinking Cognitive Health: The Atrial Fibrillation-Dementia Link
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Uncovering a Hidden Risk: The Link Between CDK4/6 Inhibitors and Jaw Bone Health
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Identification and Functional Characterization of RAB32 Ser71Arg: A Novel Genetic Variant Implicated in Familial Parkinson’s Disease
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Distinctive Hyaluronan Metabolism in Epidermal Keratinocytes: Roles of HYAL1 and HAS3
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Hyperoxia-Induced Modulation of Intrapulmonary Arteriovenous Anastomoses: from Saline Contrast Echocardiography
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Protective Potential of IgE: How Allergy-Related Immune Responses Influence Glioma Risk and Survival
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HOXDeRNA’s Role in Glioblastoma: Reprogramming Astrocytes via RNA-Driven Epigenetic Modulation
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Soluble BCMA as a Key Mediator of Resistance in Anti-BCMA T-cell Therapies for Multiple Myeloma
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Regulatory Dynamics of Enamelin Expression by Msx2 controlling Enamel Formation and Biomineralization
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Daridorexant: Novel insomnia drug shows low abuse potential in comprehensive animal study
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Characterization of PIH1D3 Deficiency in Knockout Rats: Insights into Ciliopathy Mechanisms and Phenotypic Manifestations
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Melatonin: A Cosmic Shield Against Liver Dysfunction in Zero Gravity
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One-Carbon Metabolism: Formaldehyde’s Role in S-Adenosylmethionine Biosynthesis and Disease
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Deciphering APOE’s Role in Astrocyte Lipid Droplets: Implications for Alzheimer’s Disease
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How Aβ Peptides Modulate Insulin Degradation in Alzheimer’s Disease and Diabetes
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CT-KIBRA-mediated Synaptic Repair as a Therapeutic Strategy for Cognitive Restoration in Tauopathies
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New Strategy for Bone Regeneration Leverages Cooperative Interactions between Collagen Receptors to Enhance Osteoblast Differentiation of Skeletal Progenitor Cells
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Advancing Mesenchymal Stem Cell Therapies for Bronchopulmonary Dysplasia: Challenges and Prospects
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Advancing Liver Regeneration: VEGFA mRNA-LNP’s Transformative Role in Hepatocyte Conversion
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Reversible Quiescence in Adult Stem Cells: A Profound Insight into Tissue Regeneration and Disease
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The Potential of Mesenchymal Stem Cells and Extracellular Vesicles in Osteoarthritis Pain Management
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The Mysteries of Cell Rounding: AQUAPORINs and Hematopoietic Transition
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Characterization of a melanocyte progenitor population in human interfollicular epidermis
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PDGF D in the regulation of mesenchymal stem cell biology
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Is metabolite N, N-dimethylglycine a candidate drug for peripheral nerve injury repair?
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Lymphatics act as a signaling hub to regulate intestinal stem cell activity
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Growth factor Igf2bp2 controls the function of blood stem cells in early life
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Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling
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Proliferation maintains the undifferentiated status of stem cells: The role of the planarian cell cycle regulator Cdh1
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Redefining Clinical Trials for Neural Prostheses: Bridging Technological Innovation and Ethical Responsibility
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Therapeutic Neuroplasticity: Reshaping Brain Networks in Convergence Insufficiency
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Neuropilin-1: A Target for Redefining Chronic Pain Therapies Through Non-Opioid Mechanisms
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Adaptive Deep Brain Stimulation for Real-Time Control of Parkinsonian Neural Dynamics: Toward Personalized Neuromodulation
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HDAC3 Inhibition Restores Memory Updating in Aging: A Potential Therapeutic Target for Cognitive Decline
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Neural Circuitry and Neurochemical Modulation in Cognitive Function
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Shaping Minds: How Education Carves the Brain’s Landscape
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The Key Role of p75NTR in Oligodendrocyte Genesis and Brain Myelination
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Stress, Immunity, and Alzheimer’s Disease Progression: Studies in Transgenic Mouse Models
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Epigenetic Clocks and Neurodegenerative Diseases
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Synergistic Enhancement of BDNF-Mediated Neurotrophic Activities by Apigenin: Implications for Neurodegenerative Disease Therapy
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Mapping the Current Landscape of Alzheimer’s Disease Drug Development: Trends, Challenges, and Future Directions
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Synergizing adoptive cell therapy: Boosting Cancer Cell Targeting with Dual TCR/CAR Engineering
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CRISPR-ABE Mediated Correction of ASLD via Lipid Nanoparticle Delivery: A Novel Therapeutic Approach
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Gene Therapy Rescues Neural Deficits in CNTNAP1 Mutant Mice
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Gene Therapy in Sickle Cell Disease: Clonal Dynamics and Mutation Landscapes Post-Treatment
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CRISPR Breakthrough: Targeting the Achilles’ Heel of AML – A Leap Towards Precision Oncology
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New technology enables predictive design of engineered human cells
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Hair Cell Transduction Efficiency of Single- and Dual-AAV Serotypes in Adult Murine Cochleae
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Machine-learning creates better AAV gene delivery vehicles
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New Druggable Target for Pancreatic Cancer Discovered
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GM-CSF therapy inhibits chronic graft-versus-host disease via expansion of regulatory T cells
