Medicine Innovates Medicine Innovates: Delivering innovations in medicine to the world for better health and prosperity
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microRNA in exosomes and their role in Cancer
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A Pilot Study of Checkpoint Inhibitors in Solid Organ Transplant Recipients with Metastatic Cutaneous Squamous Cell Carcinoma
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Myoferlin: A skeletal muscle protein with unusual function in pancreatic cancer
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Pioneer factor Foxa2 enables ligand-dependent activation of type II nuclear receptors FXR and LXRα
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Supplementing sorafenib treatment with vitamin K could augment sorafenib anticancer action for patients with hepatocellular carcinoma
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Role of RIN1 on telomerase activity driven by EGF-Ras mediated signaling in breast cancer
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Increase in interleukin-6 levels from ADT may cause fatigue in prostate cancer patients
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Stanniocalcin 1 reversely correlates with checkpoint therapy efficacy
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Correction of the aprt Gene Using Repair-Polypurine Reverse Hoogsteen Hairpins
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MIB2 supress caspase 8-mediated cell death
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New technology enables predictive design of engineered human cells
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α-Actinin-4 regulates cancer stem cell properties and chemoresistance in cervical cancer
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Generation of Novel Diagnostic and Therapeutic Exosomes to Detect and Deplete Protumorigenic M2 Macrophage
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Detection and destruction of HER2‐positive cancer cells by Ultra Quenchbody‐siRNA complex
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Soluble CD40L activates soluble and cell-surface integrin αvβ3, α5β1, and α4β1 by binding to the allosteric ligand-binding site (site 2)
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Reduced allergic lung inflammation and airway responsiveness in mice lacking the cytoskeletal protein gelsolin
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Longitudinal monitoring of microglial/ macrophage activation in ischemic rat brain using Iba-1-specific nanoparticle enhanced MRI
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Two monomers of the complement deregulator FHR5 associate to form a compact dimer to provide new insights into CFHR5 nephropathy
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Extracellular DJ-1 induces sterile inflammation in the ischemic brain
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Biological Rationale for prevention of COVID-19 disease with BCG vaccine
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Flt3 ligand augments vaccine designed to prevent melanoma recurrence
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Origami with DNA
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Timing of Intensive Immunosuppression Impacts Risk of Transgene Antibodies after AAV Gene Therapy
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Machine-learning creates better AAV gene delivery vehicles
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Restoring Potent Antiviral Immune Responses (RePAIR) to Treat HIV Disease
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Bioresponsive microspheres for on-demand delivery of anti-inflammatory cytokines for articular cartilage repair
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Mutations in EDA and EDAR genes cause dominant syndromic tooth agenesis
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Familial Alzheimer’s disease mutations in amyloid protein precursor alter proteolysis by γ-secretase to increase amyloid β-peptides of ≥45 residues
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TMF1- A novel mediator of the Insulin regulated glucose homeostasis and normal glycemic level
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T cell-derived extracellular vesicles are elevated in essential Hypertension
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Skeletal muscle mitochondrial fragmentation and impaired bioenergetics from nutrient overload are prevented by carbon monoxide
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CAPS2 Deficiency in Autism Impairs the Release of the Social Peptide Oxytocin
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Role of Kalirin and mouse strain in retention of spatial memory training in an Alzheimer’s disease model mouse line
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Dysregulation of TRPV4, eNOS and caveolin-1 contribute to endothelial dysfunction
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α-Synuclein facilitates endocytosis by elevating the steady state levels of phosphatidylinositol 4,5-bisphosphate
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To freeze, or not to freeze, that is the question!
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Early life stress causes sex-specific changes in adult fronto-limbic connectivity that differentially drive learning
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Monitoring ribosome collisions
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Effect of Acetylation on Amyloid Beta Toxicity
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Hsp70 chaperones dissolve protein aggregates in Parkinson’s disease
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Origin of the new coronavirus
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New therapeutic targets for SARS-coV-2 rapidly identified with new computer simulations
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The C-terminal domain of yeast Atg15 has an enzymatic activity that breaks lipid membranes of unnecessary organelles
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Mature viral cathepsin is required for release of viral occlusion bodies from Autographa californica multiple nucleopolyhedrovirus-infected cells
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Striatal and nigral muscarinic type 1 and type 4 receptors modulate levodopa-induced dyskinesia and striato-nigral pathway activation in 6-hydroxydopamine hemilesioned rats
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Development of Heterobivalent Theranostic Probes Having High Affinity/Selectivity for the GRPR/PSMA
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Discovery of a new pathway used by cells to remove cellular waste
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A little worm as a model system to investigate lipoic acid metabolism
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Safety and Pharmacokinetics of High-Dose TAS-303 in Healthy Japanese Volunteers
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Nonreactive microglia are dispensable for neuronal signaling and rhythm generation in postnatal brain tissue
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ATP, the molecule of life, is dangerous when accumulates outside the cells
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Reactive astrocytes-derived GDNF plays an important role in brain protection and improvement of long-term stroke outcomes in mouse model
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The sevoflurane anesthetic affect tau spread in the brain to promote Alzheimer’s disease pathology
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SVEP1: predict future dementia risk
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Endocannabinoid system enhancement for the treatment of sphingolipid storage disorders
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Involvement of the basal nucleus of Meynert on regional cerebral cortical vasodilation associated with masticatory muscle activity
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Modulating Campylobacter jejuni virulence by changing its rRNA methylation pattern.
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Chain length of ceramide in the endoplasmic reticulum membrane is critical for sorting selectivity