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James-J.-Collins

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Breakthrough Technologies

Translation-Coupled mRNA Decay: The Role of m6A Modifications in Fine-Tuning Gene Expression
4 days ago
Harnessing Light for Precision Gene Regulation: The OptoLacI Breakthrough
2 weeks ago
Wireless Multicolor Fluorescence Imaging Implant for Real-Time Monitoring of Immune Responses in Cancer Therapy
3 weeks ago
Nonlinear Molecular Dynamics Reveal Critical Transitions in Human Aging and Disease Risk
3 weeks ago
Inhomogeneous Au2S Nanostructures for Enhanced Dual-Function Tumor Imaging and Therapy via Targeted Energy Dissipation
3 weeks ago
Tracer-Based Metabolomics Reveals Nitric Oxide Metabolic Dynamics in a 3D Microvessels-on-Chip Model of Endothelial Dysfunction
3 weeks ago
Rod-Shaped Liquid Plasticine Reactor: Advancing Photodynamic Therapy with Improved Light Absorption and Targeted ROS Delivery
3 weeks ago
Accessible Rheo-Optical Compression Assay for High-Throughput Mechanical Characterization of Cell Spheroids
3 weeks ago
Mechanisms of Vibrio Biofilm Dispersal from Microplastics Under Simulated Human Environmental Conditions
3 weeks ago
Evaluating Anti-Aging Properties of Biomimetic Elastin and Collagen in Tri-Layered Chitosan Membranes: An Alternative to Animal Testing
4 weeks ago
Revolutionizing Macrocycle Structural Determination: High-Resolution Insights via Microcrystal Electron Diffraction (MicroED)
4 weeks ago
Charge Complementary Polymersomes: Advancing Stability and Delivery Efficiency in mRNA Therapeutics
4 weeks ago

Diagnostics

Innovative Pulmonary Imaging: 3D UTE-MRI Ventilation and Flow Mapping for Enhanced Lung Function Analysis
2 weeks ago
Deep Learning-Enhanced Plasmonic Biosensor for High-Sensitivity Hepatitis B Detection: A Portable Diagnostic Platform for Point-of-Care Use
3 weeks ago
SMART-dCRISPR: Leveraging Mismatch Tolerance, Previously Seen as a Limitation, for Enhanced CRISPR-Based Genotyping
3 weeks ago
Advancement in Cancer Detection: A Leap Forward with Novel Priming Agents in Liquid Biopsies
4 weeks ago
Correlation Between Autonomic Dysfunction and Visual Field Severity in Open-Angle Glaucoma: Insights from Kiritsu-Meijin Device Analysis
4 weeks ago
Serum Biomarkers and Neuroimaging Correlates in CT-Negative Mild Traumatic Brain Injury
4 weeks ago
GHz Frequency Microfluidics-Integrated CMOS Platform for Label-Free Cellular Dielectric Spectroscopy
4 weeks ago
Development and Validation of a CRISPR-Cas12a Enhanced PTS for Sensitive and Specific Detection of Aflatoxin B1 in Food Samples
December 15, 2024

Drug Discovery

Transforming Oral Cancer Therapies: Enhanced Bioavailability and Reduced Variability with Innovative Drug Formulations
2 weeks ago
Transforming Bioequivalence Assessment with the Finite Absorption Time Concept
3 weeks ago
Targeting EGFR Drug Resistance in NSCLC: Identification of Alternative Inhibitors through Structural Analysis and Virtual Screening
4 weeks ago
RY103: A Novel IDO1 Inhibitor Targeting Immune Suppression and Angiogenesis in Glioblastoma Therapy
4 weeks ago
Unexpected Impact of Roxadustat on Thyroid Function: New Insights into HIF-PH Inhibitors in Renal Anemia
4 weeks ago
Splicing modulating small molecules perturb the entire transcriptome: implications for developing next generation therapies for spinal muscular atrophy
December 21, 2024
Comprehensive Pharmacokinetic Analysis of Brepocitinib Using a 14C-Microtracer Approach in Healthy Male Subjects: A Phase 1 ADME Study
December 19, 2024
Marine Surfactin Modulates Neutrophilic Inflammation in ARDS via FPR1 Inhibition
December 19, 2024

Translational Medicine

Accessible Rheo-Optical Compression Assay for High-Throughput Mechanical Characterization of Cell Spheroids
3 weeks ago
RRAS2: A Prognostic Biomarker Driving Postpartum Triple-Negative Breast Cancer
4 weeks ago
Comprehensive Pancreatic Cancer Risk Prediction Model Integrating Genetic, Lifestyle, and Medical History Variables: Insights from the UK Biobank
4 weeks ago
Unsupervised Machine Learning Helps Discover Patterns of Racial Disparities in Breast Cancer Patients
December 18, 2024
Matrine-DTC Hybrids: A Promising Anti-Cancer Drug Development
December 15, 2024

Precision Medicine

Advancement in Cancer Detection: A Leap Forward with Novel Priming Agents in Liquid Biopsies
4 weeks ago
Correlation Between Autonomic Dysfunction and Visual Field Severity in Open-Angle Glaucoma: Insights from Kiritsu-Meijin Device Analysis
4 weeks ago
Serum Biomarkers and Neuroimaging Correlates in CT-Negative Mild Traumatic Brain Injury
4 weeks ago
Charge Complementary Polymersomes: Advancing Stability and Delivery Efficiency in mRNA Therapeutics
4 weeks ago
Proteomic Profiling for Optimized Therapy Selection in Acute Myeloid Leukemia
December 20, 2024

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