About the author
Juha Klefström, PhD, is a Research Director in Research Programs Unit, Medical Faculty, University of Helsinki and in Biomedicum Functional Genomics Unit. Klefström’s primary research interests are in breast cancer biology, genetically engineered mouse models of breast cancer, mammary gland reconstitution techniques, ex vivo organoid cultures and recombinant viral gene transfer methods. His laboratory has established variety of three-dimensional culture systems for primary mammary epithelial and tumor organoids to explore roles and targetability of Myc, Lkb1 and cell polarity pathways in breast cancer.
Global Medical Discovery featured article: Par6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers