Significance Reference Majhi BK, Melis A. Engineering Fibroblast Growth Factor-2 (FGF2) Production in Cyanobacteria. ACS Synth Biol. 2025;14(10):3978-3989. doi: 10.1021/acssynbio.5c00388.
Read More »Significance Reference Xie J, Cao K, Liu L, Zhang L, Yang Y, Gong H, Luo H. Mn3O4 nanozyme-based anti-inflammatory therapy modulates microglial phenotype by downregulating TLR4/NOX2 expression and further alleviates Alzheimer’s disease pathology. Theranostics. 2025;15(15):7467-7488. doi: 10.7150/thno.112213.
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Significance Reference Popay TM, Pant A, Munting F, Tastemel M, Black ME, Haghani N, Dixon JR. Acute NIPBL depletion reveals in vivo dynamics of loop extrusion and its role in transcription activation. Nat Genet. 2026 Feb 16. doi: 10.1038/s41588-026-02516-y.
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Significance Figure legend: Multispecific artificial antibody created by grafting the CDRs of different antibodies onto the same gold nanoparticle via a unique goldization technology (a), which resembles the humanization technology (b). Reference Sun Y, Ni R, Liu YY, Wang H, Cao A. Towards Multispecific Anti-Gp120 Artificial Antibody. ChemMedChem. 2025;20(15):e202500287. doi: 10.1002/cmdc.202500287.
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Significance Scheme 1. A “Blind T Cells” Model to Rationalize the Ineffectiveness of Immunotherapies, and a Strategy to Reverse Ineffectiveness of Immunotherapies via Combination of the In Situ Generated Whole Cancer Cell Vaccine by NIR-I/-II/-III/-IV PDT with Immunomodulator Anti-OX40. [Image credit: ACS Nano. 2025;19(41):36129-36147. doi: 10.1021/acsnano.5c04323]. References [1]. Shanmugam M, Chiang CS, Hwang KC. 2240 nm NIR-IV Photodynamic Therapy Can …
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