Mechanism of Action

TDP43 Control of Mismatch Repair Gene Expression and Genome Stability

Significance  Reference Vincent E Provasek, Albino Bacolla, Suganya Rangaswamy, Manohar Kodavati, Joy Mitra, Issa O Yusuf, Vikas H Malojirao, Velmarini Vasquez, Gavin W Britz, Guo-Min Li, Zuoshang Xu, Sankar Mitra, Ralph M Garruto, John A Tainer, Muralidhar L Hegde, RNA/DNA-binding protein TDP43 regulates DNA mismatch repair genes with implications for genome stability, Nucleic Acids Research, Volume 53, Issue 18, 14 October …

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Age-dependent ER remodeling through selective autophagy across tissues

Significance  Figure legend: Differential enrichment of ER subdomain markers between tissues Reference Donahue EKF, Hepowit NL, Ruark EM, Mulligan AG, Keuchel B, Urban ND, Peng L, Stephens S, Johnson DJ, Wallace NS, Jackson LP, Ellisman MH, Arrojo E Drigo R, Folkmann AW, Truttmann MC, MacGurn JA, Burkewitz K. ER remodelling is a feature of ageing and depends on ER-phagy. Nat …

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