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Key Drug Discovery Articles

Combinatorial treatment of CD95L and gemcitabine in pancreatic cancer cells induces apoptotic and RIP1-mediated necroptotic cell death network

January 25, 2016 Key Drug Discovery Articles Comments Off on Combinatorial treatment of CD95L and gemcitabine in pancreatic cancer cells induces apoptotic and RIP1-mediated necroptotic cell death network

Design and synthesis of 2-phenylnaphthalenoids and 2-phenylbenzofuranoids as DNA topoisomerase inhibitors and antitumor agents

January 25, 2016 Key Drug Discovery Articles Comments Off on Design and synthesis of 2-phenylnaphthalenoids and 2-phenylbenzofuranoids as DNA topoisomerase inhibitors and antitumor agents

The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells

January 25, 2016 Key Drug Discovery Articles Comments Off on The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells

PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice

December 10, 2015 Key Drug Discovery Articles Comments Off on PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice

Conjugated Polythiophene for Rapid, Simple, and High-Throughput Screening of Antimicrobial Photosensitizers

November 24, 2015 Key Drug Discovery Articles Comments Off on Conjugated Polythiophene for Rapid, Simple, and High-Throughput Screening of Antimicrobial Photosensitizers

Resveratrol inhibits rhinovirus replication and expression of inflammatory mediators in nasal epithelia

November 24, 2015 Key Drug Discovery Articles Comments Off on Resveratrol inhibits rhinovirus replication and expression of inflammatory mediators in nasal epithelia

Prevention of allergic rhinitis by ginger and the molecular basis of immunosuppression by 6-gingerol through T cell inactivation

November 24, 2015 Key Drug Discovery Articles Comments Off on Prevention of allergic rhinitis by ginger and the molecular basis of immunosuppression by 6-gingerol through T cell inactivation

Nisin Synergizes with Cisplatin to Induce Apoptosis in HNSCC cells that are Highly Resistant to Ionizing Radiation and Cisplatin

November 12, 2015 Key Drug Discovery Articles Comments Off on Nisin Synergizes with Cisplatin to Induce Apoptosis in HNSCC cells that are Highly Resistant to Ionizing Radiation and Cisplatin

The effects of (-)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER)

November 12, 2015 Key Drug Discovery Articles Comments Off on The effects of (-)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER)

Targeting MYCN IRES in MYCN-amplified neuroblastoma with miR-375 inhibits tumor growth and sensitizes tumor cells to radiation

November 12, 2015 Key Drug Discovery Articles Comments Off on Targeting MYCN IRES in MYCN-amplified neuroblastoma with miR-375 inhibits tumor growth and sensitizes tumor cells to radiation

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