by Priti | Jan 29, 2019 | Disease Understanding |
Significance In recent years, overexpression-based approaches have been developed to monitor the spatiotemporal localization and activity of various intracellular factors in real time. These approaches often rely on the immunofluorescence labeling of fixed cells and...
by Priti | Jan 16, 2019 | Disease Understanding |
Significance Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder that leads to abnormal blood vessel formation in the mucous membranes, skin and organs such as the brain, lungs and liver. This genetic disorder affects 1 in 5000...
by Priti | Jan 16, 2019 | Disease Understanding |
Significance The increased risk of liver cirrhosis, liver-related morbidities and mortalities has been attributed to the excessive accumulation of myofibroblasts in injured liver cells (a.k.a. progressive liver fibrosis). Liver injury triggers the...
by Priti | Dec 10, 2018 | Disease Understanding |
Significance Epidermal Growth Factor Receptor (EGFR) is a member of the type I transmembrane tyrosine kinase-associated receptors; other members of this superfamily include ErbB2, ErbB3, and ErbB4. The overexpression of ErbB members mediates the progression of...
by Priti | Oct 11, 2018 | Disease Understanding |
Significance The increasing need to understand the role of cannabinoid CB2 receptor (CB2R), in the development of neuropsychiatric disorder is due to its association with different forms of anxiety-like and depression-like behaviors. Despite the availability of...
by Priti | Aug 13, 2018 | Disease Understanding |
Significance Percutaneous coronary intervention with implantation of stent is the most popular treatment method for coronary artery disease. The implementation of stents led to decreased effect of acute elastic recoil as well as occlusive dissection on restenosis....
