by Priti | Jun 25, 2018 | Disease Understanding |
Significance Although several pathogenic fungi can be found in the surrounding environment, Candida, which is a natural human commensal, is found in our own gastrointestinal tract. However, these organisms can become sources of deadly infection in immune-compromised...
by Saleem | Jan 31, 2018 | Disease Understanding |
Significance An international team of scientists have confirmed the discovery of a major cause of dementia, with important implications for possible treatment and diagnosis. Professor Garth Cooper from The University of Manchester, who leads the Manchester team, says...
by Saleem | Jan 28, 2018 | Disease Understanding |
Significance Although men with prostate cancer usually respond to standard treatment with hormone therapy or chemotherapy, many will eventually experience progression or recurrence despite treatment—particularly those with high-risk or aggressive forms of the disease....
by medinnovates | Oct 1, 2016 | Disease Understanding |
Significance Model of the pathway for the interplay of JNK and mitochondria in cell death. JNK is initially activated by the MAPK cascade either extrinsically by receptor signaling or intrinsically by organelle stress emanating from mitochondria, endoplasmic...
by medinnovates | Sep 29, 2016 | Disease Understanding |
The genome is constantly confronted with the risk of DNA damage by various factors such as hazardous metabolic byproducts, carcinogens, and UV radiation. Nucleotide excision repair (NER) is one of DNA repair systems that organisms have evolved to protect the genome....
by medinnovates | Jun 17, 2016 | Disease Understanding |
Protein-protein interactions are of great importance for virtually all biological processes and whether transient or stable, they support the formation of multimeric complexes. Monitoring such interactions may help us characterize signaling and trafficking behaviours...
