Disease Understanding Archives - Page 2 of 12

Denitrosylation Control of Lipid Synthesis Through Cytoskeletal and Enzymatic Targets

July 8, 2026 Disease Understanding Comments Off on Denitrosylation Control of Lipid Synthesis Through Cytoskeletal and Enzymatic Targets

Significance Figure legend: The protein denitrosylase SCoR2 regulates lipogenesis and fat storage Reference Venetos NM, Stomberski CT, Zhou HL, Qian Z, McLaughlin PJ, Bansal PK, Feczko J, Bederman I, Nguyen H, Hausladen A, Schindler JC, Grimmett ZW, Brunengraber H, Premont RT, Stamler JS. The protein denitrosylase SCoR2 regulates lipogenesis and fat storage. Sci Signal. 2025 Dec 23;18(918):eadv0660. doi: 10.1126/scisignal.adv0660.

β-Blockers as Potential Modulators of Huntington’s Disease Onset and Progression

July 2, 2026 Disease Understanding Comments Off on β-Blockers as Potential Modulators of Huntington’s Disease Onset and Progression

Nav1.5-Mediated Sodium Influx Drives Breast Cancer Metastasis Through Glycolytic Acidification

June 29, 2026 Disease Understanding Comments Off on Nav1.5-Mediated Sodium Influx Drives Breast Cancer Metastasis Through Glycolytic Acidification

Squalene Peroxidation in Acne Vulgaris: Linking Sebum Oxidation to Inflammation and Comedogenesis

June 29, 2026 Disease Understanding Comments Off on Squalene Peroxidation in Acne Vulgaris: Linking Sebum Oxidation to Inflammation and Comedogenesis

Impact of APOE Locus on Aging-Related Mitochondrial Function in Alzheimer’s Disease and Longevity

July 10, 2025 Disease Understanding Comments Off on Impact of APOE Locus on Aging-Related Mitochondrial Function in Alzheimer’s Disease and Longevity

Structural and Functional Insights into ORCA’s Role in Chromatin Organization and DNA Replication Initiation

July 7, 2025 Disease Understanding Comments Off on Structural and Functional Insights into ORCA’s Role in Chromatin Organization and DNA Replication Initiation

SOCS1 Regulation of Hepatic Stellate Cell Activation: Implications for Liver Fibrosis and Hepatocellular Carcinoma Development

July 5, 2025 Disease Understanding Comments Off on SOCS1 Regulation of Hepatic Stellate Cell Activation: Implications for Liver Fibrosis and Hepatocellular Carcinoma Development

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